Abstract
The beginning of research on TBE in Germany was influenced and inspired by the results and developments of TBE research in the former Czechoslovakia. There, TBE virus was detected in the Czechoslovak Republic in 1948. In Germany, the first evidence of the presence of TBE virus was found by Sinnecker and his group in the former German Democratic Republic (GDR). The first virus strains were isolated also by Sinnecker’s group in the early 1960s. In the former Federal Republic of Germany (FRG), TBE research started with research on TBE virus in the region of Franconia by Scheid and Ackermann. In the region of Lower Franconia, a virus was isolated which was called “Zimmern Virus'' after the location of the isolation. Unfortunately, all these virus strains were lost but it can be assumed that they all belonged to the Western (European) subtype of TBE virus.
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