Abstract
A trial was conducted to evaluate the effect of live yeast culture Saccharomyces cerevisiae (SC) on the glutathione content of liver and gastric mucosa. Twenty male New Zealand white rabbits, aged 5 weeks, were studied in 2 groups. Groups were control (basal diet) and SC (added 3 g/kg diet). The experiment lasted for 90 days. Blood samples were obtained by ear venipuncture on the 90th day. According to results, glutathione concentration of both liver and gastric mucosa were increased by the addition of SC (p<0.05). S.cerevisiae may be used for antioxidant supplement due to the maintain of glutathione metabolism. SC intake may contribute to enhanced quality of life by increasing antioxidant protection. More studies would be necessary to elucidate the effects of yeast culture supplementation on concentration of glutathione in animals and humans.
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