Tavşanlarda Saccharomyces cerevisiae ve Spirulina platensis’ in glutatyon ve lökosit sayısı üzerine etkileri

Abstract

Glutathione is the important molecule for protecting health, especially crucial for body detoxification system. A feeding trial was conducted to evaluate the effect of natural additives such as live yeast culture Saccharomyces cerevisiae (SC) and microalgae Spirulina platensis (SP) on the glutathione and leukocytes counts of rabbits. Forty male New Zealand white rabbits, aged 5-6 weeks, were studied in 4 groups. Treatments were control group, SC (added 3 g/kg diet), SP (added 5% of the diet) and, SC and SP (added 3 g/kg diet and added 5% of the diet) respectively. The experiment lasted for 90 days and the blood samples were obtained by ear venipuncture on the 90th day. In conclusion, according to the results of this study, although not statistically significant, supplementing rabbit with S. cerevisiaea or S. platensis had increased on glutathione values. Gutathione tend to be positively correlated with the addition of SC or SP. No significant difference in white blood cell counts was evidenced, even if lymphocyte counts tended to increase, and neutrophile counts to decrease in rabbits fed SC or SC+SP. The determination of biological consequences (antioxidant potential, resistance to diseases, improvement of nutritional status ) requires further investigations.Keywords: Saccharomyces cerevisiae, Spirulina platensis, glutathione, leukocyte.____________________________________________________________________1,4Uludag University, Faculty of Veterinary, Department of Physiology, TR-16059, Bursa, TURKEY 2Tekirdağ Namık Kemal University, Faculty of Veterinary, Department of Physiology, Tekirdağ, 3 Uludağ University, Faculty of Medicine, Department of Medical Biochemistry, Bursa ,TURKEY