Abstract
Targeting the endocannabinoid system to treat haunting traumatic memories
Highlights
One of the core symptoms in posttraumatic stress disorder (PTSD) is the traumatic memory that constantly haunts the patient
PTSD is a paradoxical disorder of memory—on the one hand, intrusive recollections for certain aspects of the event and, on the other hand, amnesia for other important aspects (Ehlers et al, 2004)
The authors reviewed the literature suggesting that eCBs have an essential role in maintaining emotional homeostasis (Haller et al, 2002, 2004; Lutz, 2007; Niyuhire et al, 2007; Hill and Gorzalka, 2009; Moreira and Wotjak, 2010; Parolaro et al, 2010) and in modulating memory consolidation, retrieval and extinction (Marsicano et al, 2002; Niyuhire et al, 2007; Marsicano and Lafenetre, 2009; Atsak et al, 2012a; Campolongo et al, 2013)
Summary
One of the core symptoms in posttraumatic stress disorder (PTSD) is the traumatic memory that constantly haunts the patient. The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD) by Trezza, V., and Campolongo, P.
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