Abstract

Cancer medically known as malignant neoplasm is a group of different diseases all involving unregulated cell growth due to defects in the genetic makeup of two types of genes, i.e. oncogene, which drive the growth of cancer cells and tumor suppressor genes which prevent cancer from developing. Cancer is detected in a number of ways, including symptoms, screening tests, medical imaging and is usually treated with chemotherapy, radiation therapy and surgery. With the advancement in medical sciences, targeted cancer therapy has got lot of importance which has many benefits, comforts and patient friendly as compared to conventional therapies. This review gives an insight of the various targeted therapies, their role and impact in treatment of various types of cancers. Targeted cancer therapies like monoclonal antibodies, nanoparticle-aptamer bioconjugates, oligopeptide-based, folate-based, AdNectins, microfluidics and nanotechnology approaches have led to deliver target- oriented toxic drugs to specific cancer cells.DOI: http://dx.doi.org/10.3126/ijls.v6i1.6085

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