Abstract
Diabetes mellitus is a chronic disease affected by scarcity in the production of insulin. In the present study, we used the bioinformatics approach to examine the possible inhibitory abilities of phytochemical constituents of Tecoma stans towards thioredoxin interacting protein. All the phytochemicals showed good binding attraction to the binding pocket of thioredoxin-interacting protein. pkCSM server was used to detect pharmacodynamics, pharmacokinetics and toxicological profiles of phytochemical compounds. The amino acids Lysin 117, Lysin 115 and Glycine 119 were exhibited as the key residues for the phytochemicals of Tecoma stans and binding to inhibit the thioredoxin-interacting protein. However further studies are needed to identify the efficacies and activities of Tecoma stans compounds against thioredoxin-interacting protein.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
