Abstract
Nanoparticles having magnetic and fluorescent properties could be considered as a gift to materials scientists due to their unique magneto-optical qualities. Multiple component particles can overcome challenges related with a single component and unveil bifunctional/multifunctional features that can enlarge their applications in diagnostic imaging agents and therapeutic delivery vehicles. Bifunctional nanoparticles that have both luminescent and magnetic features are termed as magnetic nanolights. Herein, we present recent progress of magneto-fluorescent nanoparticles (quantum dots based magnetic nanoparticles, Janus particles, and heterocrystalline fluorescent magnetic materials), comprehensively describing fabrication strategies, types, and biomedical applications. In this review, our aim is not only to encompass the preparation strategies of these special types of magneto-fluorescent nanomaterials but also their extensive applications in bioimaging techniques, cancer therapy (targeted and hyperthermic), and sustained release of active agents (drugs, proteins, antibodies, hormones, enzymes, growth factors).
Highlights
Nanotechnology is a rapidly developing area, involving the fabrication and usage of nano-scaled materials and devices
For ex situ technique, the nanoparticles were prepared in two consecutive steps; initially they were prepared followed by some surface decoration of ligand modi cation
Magneto fluorescent quantum dots (MFQDs) are permeable/attach to cancer cells which enhance the effect of bio-marking of the tumors
Summary
Dr Poushali Das is a senior postdoctoral research fellow at Bar Ilan Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Israel She has completed PhD degree in 2019 from Indian Institute of Technology Kharagpur, India. Further interesting applications of the MFNPs consist of cytometry, cell tracking, and magnetic separation, which could be controlled and monitored using confocal or uorescent microscopy and MRI.[48,49] these intriguing nanostructures have appealed a lot of consideration in recent years
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