Abstract

Magnetic Janus particles have been studied extensively for medical and biological applications owing to their controllable mobility in fluid media. In this work, we report a novel microfluidic device designed for the synthesis of magnetically anisotropic Janus particles made of poly(ethylene glycol) diacrylate and embedded with magnetic iron oxide nanoparticles. Our method consists of a droplet generation step followed by magnetic separation using an external magnetic field and ultraviolet polymerization. The synthesized particles exhibit a monodisperse size distribution with a standard deviation of less than 3.5%, which is among the best size distributions obtained in the literature for magnetic Janus particles. The anisotropic magnetic property of the particles enable them to rotate about their own axes in the presence of an external magnetic field, introducing another degree of freedom to their motion. This microfluidic technique is simple, one-step, and versatile, offering control over the size distribution to synthesize magnetically anisotropic Janus particles.

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