Tactile Sliding Behavior of R2R Mass-Produced PLLA Nanosheet towards Biomedical Device in Skin Applications.

Sheng Zhang,Yoshitomo Kai,Yuta Sunami

doi:10.3390/nano8040210

Abstract

In this research, sliding friction was measured between the fingertip and nanosheet on a silicon substrate under two conditions: dry and wet. By using a force transducer, the tactile friction force and applied load were measured. According to the experimental results, the relationship of friction force and applied load exhibits a positive correlation under both dry and wet conditions. In addition, the nanosheets are able to reduce the friction force and coefficient of friction (COF) compared to the reference sample, especially under the wet condition. Under the assumption of a full contact condition, the estimated contact area increases with larger applied loads. Furthermore, based on the wear observation, the skin sliding performance caused slight abrasions to the surface of the nanosheet samples with a mild wear track along the sliding direction. Overall, the sliding behavior between the skin and nanosheet was investigated in terms of friction force, COF, applied load, contact area, and wear. These findings can contribute to the nanosheet-related research towards biomedical devices in skin applications.

Highlights

Ultrathin films, commonly known as nanosheets, possess a tremendously large surface-area-tothickness ratio that has attracted increasing attentions over a great range of research fields [1]
We investigate the sliding behavior and the tribological mechanism of R2R mass-produced poly(L-lactic acid) (PLLA) nanosheets interacting with skin in vivo
Since the sliding direction was along the x-axis, the measured force on the x-axis is indicated as the friction force generated between the testing finger and sample

Summary

Introduction

Commonly known as nanosheets, possess a tremendously large surface-area-tothickness ratio that has attracted increasing attentions over a great range of research fields [1]. Different from their bulk state, the two-dimensional (2D) shapes of the nanosheet state exhibit unique physical, chemical, and electronic properties, revealing potential applications in various areas, e.g., catalysis, sensing, biomedical fields, etc. The excellent adhesiveness of PLLA nanosheets can stabilize the wound area without eliciting an inflammatory response. Okamura et al conducted several research experiments using a PLLA nanosheet as patchwork treatment for burn wounds with no assistance of any adhesive reagent [7]. The patchwork function acted as an excellent barrier to prevent infection during the treatment of burns

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Discussion

Conclusion