Abstract
Impulsivity, a major hallmark of addiction and other disorders characterized by the tendency to act without forethought or conscious judgment. Both clinical and preclinical studies have linked trait impulsivity with fatty acid amide hydrolase (FAAH), the enzyme responsible for the degradation of the endogenous cannabinoid, anandamide. Using a novel positron emission tomography (PET) radiotracer for FAAH, [11C]CURB, the present study investigated the relationship between Barratt Impulsiveness scores and FAAH brain levels in healthy individuals.
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