不同的長跑量與身體質量指數對老年男性T淋巴球分泌白血球間素─2和白血球間素─4的影響

Abstract

The purpose of this study was to compare the effect of different long distance running volume and body mass index on secretion of Interleukin-2（Il-2）and Interleukin-4（Il-4）from T Lymphocyte in the elderly men. Twenty-three male subject were selected and divided into high long distance running volume （HLDR）, low long distance running volume（LLDR）,and control（C）group according to their running distance；high body mass index（HBMI）,middle body mass index（MBMI），and low body mass index（LBMI）group according to their body mass index. Blood sample was taken for measurement of Il-2 and Il-4 secretion from mononuclear cell. One way ANOVA was used to compare the difference among the group. The following results were found:1）The secretion of Il-2 from T Lymphocyte of LLDR（21.84±2.05pg/ml）was significantly higher than HLDR（19.32±0.63 pg/ml）（P＜0.05），there was no significant different between LLDR and C，HLDR and C in the secretion of Il-2.The secretion of Il-4 from T Lymphocyte of LLDR（19.16±1.48 pg/ml） was significantly higher than HLDR（16.22±0.92 pg/ml）and C（16.30±0.52 pg/ml）（P＜0.05），there was no significant different between HLDR and C in the secretion of Il-4 from T Lymphocyte .2）Secretion of Il-2 from T Lymphocyte of LBMI（21.53±1.64 pg/ml）was significantly higher than MBMI（19.29±0.62 pg/ml）and HBMI（19.43±0.81 pg/ml）（P＜0.05）,there was no significantly different between MBMI and HBMI in the secretion of Il-2；The secretion of Il-4 from T Lymphocyte of LBMI（18.14 ±1.65 pg/ml）was significantly higher than MBMI（15.95 ±0.74 pg/ml）and HBMI（16.21±0.40 pg/ml）（P＜0.05），there was no significantly different between HBMI and MBMI in the secretion of Il-4. In conclusion, moderate long distance running volume and low body mass index was advantageous to regulation of adaptived immune system in the elderly men.