Abstract
Systems metabolic engineering, industrial biotechnology and microbial cell factories
Highlights
Cell factories have been largely exploited for the controlled production of substances of interest for food, pharma and biotech industries
How much limited is the economic feasibility of microbial production? Have the cell factories reached a plateau in their development? Is there more room for further exploitation of the microbial production?
Creation of new metabolic pathways and fine tuning of the existing ones have become possible [8,15]. This is already allowing the production of substances so far reluctant to microbial production under industrial requirements and under cost-effective processes, allowing us to overcome limitations of microbial cell factories
Summary
Systems solutions by lactic acid bacteria: from paradigms to practice. Teusink B, Bachmann H, Molenaar D: Systems biology of lactic acid bacteria: a critical review. Rodriguez-Carmona E, Villaverde A: Nanostructured bacterial materials for innovative medicines.
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