Abstract

A two-year-old, 3.9 kilogram, male castrated, domestic shorthair cat presented to The Ohio State University Veterinary Medical Center for acute onset neurological signs. During hospitalization, he was diagnosed with an ACVIM stage B1 hypertrophic cardiomyopathy (HCM) phenotype on echocardiogram. His clinical signs acutely worsened, including seizure activity and panting, and he was euthanized. Necropsy revealed the histopathologic diagnosis of systemic reactive angioendotheliomatosis (SRAE), which notably severely affected the myocardium. In this case report, we present the ante-mortem diagnostic results and post-mortem necropsy results of this rare condition in cats. This case demonstrates that echocardiographic assessment of the heart in cats affected by SRAE may lead to the false diagnosis of HCM, and thus should be considered as a differential diagnosis in cats with symmetrical LV wall thickening on echocardiography.

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