Abstract
THE clinical features of fifty successive patients with systemic lupus erythe matosus (SLE) presenting to a tertiary referral rheumatology department were examined. Forty-nine patients were born in Ireland, giving an opportunity to seek racial or environmental factors which might modify disease expression and clinical course. However, mean age at onset, clinical features and five year survival did not differ from other Caucasion populations reported in the literature. This study failed to provide evidence which might suggest that environmental or genetic factors influence clinical course of SLE in Ireland.
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