Abstract
To the Editor: In the review article about systemic immunoglobulin light chain (AL) amyloidosis, Sanchorawala (June 27 issue)1 leads readers by the hand on a journey through pathogenesis, diagnosis, risk stratification, and management. We were surprised, however, that the author did not mention a typical pattern of lung involvement that is seen on high-resolution computed tomography (CT) in persons with light-chain deposition disease: cystic lung disease, which is associated with nodules (which are small, irregular, and multiple and can be in one or both lungs), and lymphadenopathy. Cyst formation is believed to correspond to dilatation of small bronchi.2,3 Although lung .
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