Abstract

Abstract This systematic review and meta-analysis aims to elucidate the association between early post-traumatic seizures (EPTS) and the development of post-traumatic epilepsy (PTE) following traumatic brain injury (TBI) in adults. The study will synthesize evidence from multiple sources to identify risk factors for EPTS and PTE, and assess the prognostic significance of EPTS in predicting PTE. By providing a comprehensive analysis of the EPTS-PTE relationship and associated risk factors, this review seeks to inform more effective prevention, evaluation, and management strategies for TBI patients at risk of developing post-traumatic seizures and epilepsy.

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