Abstract

Abstract Infectious diseases have caused the death of many people throughout the world for centuries. For this purpose, many researchers have investigated these diseases for establishing new treatment and protective measures. The most important of these is HIV disease. In this study, an HIV infection model of CD4+ T cells is handled comprehensively with the newly defined Atangana-Baleanu (AB) fractional derivative. The existence and uniqueness of the solutions for fractionalized HIV disease model with the new derivative by considering the Arzela-Ascoli theorem.

Highlights

  • Over the past 50 years, the Human Immunodeficiency Virus (HIV) has become a lethal disease that affects the world in a global sense

  • According to the researches conducted by the World Health Organization (WHO) worldwide, approximately 35 million people were affected by this disease, 940000 people died from HIV-related causes at the end of 2017

  • We have examined the system response of the HIV infection model in [1] by modeling the AB fractional derivative in Caputo sense

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Summary

Introduction

Over the past 50 years, the Human Immunodeficiency Virus (HIV) has become a lethal disease that affects the world in a global sense. According to the researches conducted by the World Health Organization (WHO) worldwide, approximately 35 million people were affected by this disease, 940000 people died from HIV-related causes at the end of 2017. These statistics are inevitably increasing in spite of all the precaution taken over the years. By the above motivation, we will handle an HIV infection model of CD4+T cells, considered in [1], for investigating the system components under the effect of non-singular kernel derivative which is defined in [12] For this purpose, the rest of the paper is divided into 4 Sections.

Basic definitions and preliminaries
Model description
Existence and uniqueness of the solutions
Concluding remarks
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