Abstract
Article Title and Bibliographic Information Platelet-Derived Growth Factor Stimulates Bone Fill and Rate of Attachment Level Gain: Results of a Large Multicenter Randomized Controlled Trial Nevins M, Giannobile WV, McGuire MK, Kao RT, Mellonig JT, Hinrichs JE, et al. J Periodontol 2005;76(12):2205-15 Level of Evidence 1a Purpose/Question 1. Among adults with chronic periodontitis and infrabony pockets, is synthetic platelet-derived growth factor (rhPDGF–BB) plus bone substitute (β-tricalcium phosphate [β-TCP]) more effective in regeneration than bone substitute alone? 2. Among adults with chronic periodontitis and infrabony pockets, is 0.33 mg/mL rhPDGF–BB plus β-TCP more effective in regeneration than 1.0 mg/mL rhPDGF–BB plus β-TCP? Source of Funding Industry: BioMimetic Therapeutics, Franklin, Tennessee Type of Study/Design Multicenter Triple-Blinded Randomized Controlled Trial
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call