Synthesis, Spectral Studies, and Antimicrobial Evaluation of Antimony(III) Tri[3(2′-hydroxyphenyl)-5-(4-substituted Aryl]pyrazolinate

Abstract

The synthesis and structure of antimony(III) tripyrazolinates complexes with bidentate N,O, Schiff base pyrazoline ligands are reported. Four new coordination complexes incorporating antimony have been synthesized and characterized by spectroscopic methods (IR, 1 H NMR, 13 C NMR), molecular weight, and elemental analysis. Novel complexes of the type Sb(C 15 H 12 N 2 OX) 3 have been synthesized in dry benzene by the reaction of SbCl3 and the sodium salt of pyrazoline, NaC 15 H 12 N 2 OX, [where X = H (1), CH 3 (2), OCH 3 (3), and Cl (4)] in 1:3 molar ratio. The 3(2′ -hydroxyphenyl)-5-(4-substituted aryl) pyrazoline behaves as a bidentate ligand and coordinates to antimony through oxygen and nitrogen atoms, leading to distorted pentagonal bipyramidal structure. The antimicrobial properties of antimony are greatly enhanced when antimony is combined with this pyrazoline ligand. Compounds were screened against different bacteria (B. licheniformis and K. pneumonia) and fungi (Aspergillus niger and Penicillium notatum), and show potential activities.