Abstract
Novel metal complexes of Co(II) and Ni(II) have been prepared from reaction of their different salts with previously prepared ligand (L) namely (N,N'-(1,2-phenylene)bis(2-aminobenzamide). Synthesis ligand and its metal (II) complexes (1-5) were reported and characterized with the help of analytical and physiochemical analysis as elemental, IR spectra, thermal (TG/DTG), UV-Vis, magnetic susceptibility and molar conductance in DMF, On the view of the previous data and measurements, the structure and composition species behave as mononuclear and octahedral geometry has been proposed for all the complexes except for complex (1) adopted tetrahedral structure. Furthermore, the in vitro antibacterial Staphylococcus aureus (ATCC 25923) as Gram-positive strain, Escherichia coli (ATCC 25922) as Gram-negative strain and antifungal Candida albicans (ATCC 10231) have been studied for all samples using disc diffusion method against Ampicillin and Fluconazole as positive controls, respectively. The results show that complexation facilitates the activity of most studied metal complexes than the free ligand.
Highlights
During the last several years, coordination chemistry has been considerably enriched due to the synthesis and characterization of a large number ligands and their transition metal complexes in which the metal is coordinated by sulfur, nitrogen and oxygen [1, 2]
Coordination chemistry of transition metal complexes has been the subject of interest, because of the complexities associated with many variable factors as oxidation states, variety of geometries around the metal ions, donating properties of ligands and their influence on spectral, catalytic and biological properties of metal ions [3,4,5,6,7]
In the view of interest and importance of these ligands, we reported the synthesis of novel metal complexes of Co(II) and Ni(II) by reaction of their different salts with (N,N'-(1,2-phenylene)bis(2aminobenzamide)
Summary
During the last several years, coordination chemistry has been considerably enriched due to the synthesis and characterization of a large number ligands and their transition metal complexes in which the metal is coordinated by sulfur, nitrogen and oxygen [1, 2]. Transition metal complexes introduce large and wide spectrum of biological, enantioselective catalytic and therapeutic activity. Many metal complexes were used as antimicrobial, antitumor and antifungal agents [2]. The success of such metal complexes for enantioselective catalysis is largely dependent on the structure and electronic properties of the chiral ligands [11]. The ligand and its complexes have been characterized with the help of analytical, spectral
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