Synthesis, Spectral Characterization and Antimicrobial Evaluation of 1- Hydroxy-2-acetonaphthone Schiff Base and their Fe(II), Mn(II) Metal Complexes

Abstract

Herein, we are reporting synthesis, characterization and antimicrobial activity of two novel Fe(II) and Mn(II) Schiff base metal complexes. These metal complexes were characterized by UV-Vis., FT-IR, NMR, LCMS, ESR and powder X- ray diffraction study. UV-Vis spectra resulted in more than 400 nm transition peak that confirms formation of metal ligand charge transfer. FT-IR confirms the formation of unsymmetrical Schiff base ligand and its complex obtained by using naphthol -OH and azomethine -C=N- group. 1H-NMR spectral data confirms the formation of Schiff base ligand and its complexes. From the XRD study, we approve that the formed Fe(II) and Mn(II)complexes show orthorombic crystal system. ESR spectra of Mn(II) complex suggested an octahedral geometrical arrangement surrounding to the central metal ion. Antimicrobial activity of Schiff base and their metal complexes was observed for two gram negative E. coli, P. aeruginosa and two-gram positive S. aureus and B. subtilis bacterial strains. Antifungal activity of Schiff base and their metal complexes was also observed for two fungi C. albicans and A. niger. It was observed that the formed complexes exhibit higher activity than the compared Schiff base.