Abstract

A Schiff base ligand derived from salicylaldehyde and 2, 4-dinitrophenylhydrazine was synthesized, along with its Co(II) and Ni(II) complexes (CoL2 and NiL2). These compounds were characterized by melting point/decomposition temperature, solubility, molar conductance, magnetic susceptibility, infrared analysis, and UV-visible spectrophotometry. The metal-ligand ratio in the complexes is 1:2. All complexes exhibited low molar conductance values (5.2-11.0), indicating their non-electrolytic nature. The synthesized ligand and its metal (II) complexes were evaluated for antibacterial activity against five bacterial isolates (Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Staphylococcus aureus) and three fungal isolates (Fusarium solani, Aspergillus fumigatus, and Candida albicans) using the well diffusion method. The results demonstrated that the metal complexes exhibited greater antimicrobial activity compared to the Schiff base ligand. Keywords: Isolates, Conductance value, Synthesis, Non-electrolytic, Fusarium solani

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