Abstract
AbstractSyntheses of novel fused furo, dioxolo and dioxino derivatives of coumarin are carried out through the reaction of 7,8‐dihydroxycoumarin derivative 1 with α‐halocarbonyl compounds (α‐haloketone, α‐haloester and chloroacetyl chloride) and 1,2‐dichloroethane. The photooxygenation of synthesized furocoumarin derivative was performed and the affinity of furocoumarin derivative towards DNA was evaluated and compared with 8‐methoxypsoralen (8‐MOP), which extensively used in photochemotherapy.
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