Abstract
An efficient synthesis of 4,7‐dibromo[1,2,5]thiadiazolo[3,4‐d]pyridazine is reported. For the first time, palladium‐catalysed cross‐coupling reactions of a dihalo derivative was found to be a powerful tool for the selective formation of various mono‐ and diarylated derivatives of strongly electron‐accepting heterocycles. Suzuki–Miyaura coupling can be successfully employed for the preparation of mono‐arylated derivatives, whereas Stille coupling is useful for both mono‐ and diaryl(hetaryl)ated heterocycles. The cyclic voltammogram showed that 4,7‐dibromo[1,2,5]thiadiazolo[3,4‐d]pyridazine can be easily oxidized to form a stable anion radical. The calculated values of ELUMO confirmed that [1,2,5]thiadiazolo[3,4‐d]pyridazine is one of the strongest electron–acceptor systems.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
