Abstract
The metal-catalyzed cross-coupling reaction of oxazoles is discussed in this review. Initially, preparation of metallated oxazoles (oxazole-M) and halo- and trifloyloxazoles (oxazole-X) is outlined. After that, comprehensive examples of Negishi, Stille, Suzuki-Miyaura, and Sonogashira reactions at each three position in oxazoles (C-2, C-4, and C-5) are detailed with showing both types of reactions [route A (reaction of oxazol-M and Ar-X) and route B (reaction of oxazole- X and Ar-M)]. Keywords: Oxazoles, cross-coupling, Negishi reaction, Stille reaction, Suzuki-Miyaura reaction, Sonogashira reaction
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.