Abstract

New 5-nitroimidazoles bearing a tetrasubstituted ethylenic double bond in 2-position were synthesized in high yields by the reaction of secondary nitronate anions with a new reductive alkylating agent, 1-methyl-2-trichloromethyl-5-nitroimidazole. Consecutive SRN1 and ERC1 mechanisms were followed in these processes.

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