Abstract
The invention relates to tert-Butyl 4-bromo-4-formylpiperidine-1-carboxylate and a series of derivatives, which can be used to treat tumor viruses. This research mainly describe a synthesis route of key intermediate for synthetizing CDK9 inhibitors and Ibrutinib. The synthesis route is mainly consisit of three steps of Boc anhydride protection, oxidation and reduction. This synthesis route provides some valuable references and experimental basis for the synthesis of CDK9 inhibitors and Ibrutinib.
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