Abstract
Synthesized visnagin-9-sulfonyl esters underwent cleavage of their pyran ring upon treatment by hydroxylamine hydrochloride, hydrazine hydrate and primary amines. Reaction of visnagin-9-sulfonyl chloride 1 with alcohols or phenol gave the corresponding sulfonate derivatives 2, that were treated with hydroxylamine hydrochloride, anilines or hydrazine derivatives to give the corresponding compounds 3–5, respectively. The obtained products demonstrated potent anti-HIV activity.
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