Abstract

A series of new2-pyridone derivatives was synthesized through reaction of the a,?-unsaturated carbonyl compounds with malononitrile in refluxing ethanolin basic media. The a,?-unsaturated carbonyl compounds were synthesized from the reaction of the hydrazide-hydrazone with substituted benzaldehydes in presence of ethanol, and triethylamine as a base. Hydrazide-hydrazone derivative was prepared by reactions 2-cyanoacetohydrazide with4- benzylsulfonylacetophenonein refluxing ethanol. The structures of all synthesized compounds were confirmed by spectral (FT-IR, 1H NMR, 13C NMR) data.. KEYWORDS :4-(Benzylthio) acetophenone, 4-Benzylsulfonylacetophenone, 2-Cyanoacetohydrazide, Hydrazide-hydrazone, 2-Pyridone derivatives, a,?-unsaturated carbonyl compounds.

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