Abstract

This study focuses on synthesizing a hybrid micro-hydrogel with antibacterial properties by electron beam irradiation. The micro-hydrogel matrix is based on biocompatible polymer poly(vinyl)alcohol functionalized with antibacterial compounds: graphene oxide and silver nanoparticles The polymer composites were synthesized by irradiation with an electron beam at 10, 25, 50 kGy absorbed dose to form silver nanoparticles.

Highlights

  • This study focuses on synthesizing a hybrid micro-hydrogel with antibacterial properties by electron beam irradiation

  • The micro-hydrogel matrix is based on biocompatible polymer poly(vinyl)alcohol functionalized with antibacterial compounds: graphene oxide and silver nanoparticles The polymer composites were synthesized by irradiation with an electron beam at 10, 25, 50 kGy absorbed dose to form silver nanoparticles

  • This work aims to produce a multifunctional hybrid micro-hydrogel (HMH) that can mimic the biology of human tissues in terms of structure, function, and performance

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Summary

Introduction

This work aims to produce a multifunctional hybrid micro-hydrogel (HMH) that can mimic the biology of human tissues in terms of structure, function, and performance. For this reason, a poly(vinyl)alcohol (PVA) matrix was chosen and functionalized with pyrrole (Py) to improve conductivity, with graphene oxide GO and silver nanoparticles (AgNPs) as antibacterial compounds [1–3]. Polypyrrole (PPy) is often used in biomedical applications (e.g., biosensors, hydrogels, and drug delivery) because of its good biocompatibilities and environmental and thermal stability [4–6]. PPy is an electrically conductive polymer with electrical conductivity ranging between 10 and 100 s/cm [4]. PPy has the disadvantages of being brittle and mechanically unstable [5]

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