Abstract
The present work reports on the antibacterial and antioxidant activity of gold and silver nanoparticles, synthesized by an extract of the brown macroalga Sargassum muticum (SM). These nanoparticles were synthesized and fully characterized by means of UV–Vis spectroscopy and electron microscopy. These techniques confirmed that spherical nanoparticles, with mean diameters of 10.4 ± 1.2 nm for Au@SM and 41.0 ± 5.7 nm for Ag@SM, were formed. To investigate the possible role of these biomolecules in this green synthetic process, Fourier-transformed infrared spectroscopy analysis was performed before and after the synthesis of nanoparticles. Furthermore, the carbohydrate composition was examined along with other variations observed after the synthesis of nanoparticles by size-exclusion chromatography. The study of the changes observed indicated that the polysaccharide fraction of the extract plays a role in the formation of the nanoparticles as well as in their stabilization. The in vitro antioxidant activity was analyzed by the determination of the reducing power, total content of phenolic compounds and the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) scavenging activity. Lastly, the antibacterial activity was tested against three types of bacteria with different cell wall composition. In particular, Ag@SM showed good inhibitory capacity on Gram+, especially on Staphylococcus aureus with a MIC of 3.38 µg/mL.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
