Abstract

Abstract Precocene-I (1) (7-methoxy-2, 2-dimethylchromene) and precocene-II (6,7-dimethoxy-2, 2-dimethylchromene) isolated from Ageratum houstonianum plants have been shown to exhibit novel antijuvenile hormone activity1. These compounds induce precocious metamorphosis in young nymphal stages of test insects resulting thereby into unviable miniature adults showing distinct cessation of juvenile hormone mediated functions. One of the views regarding the mode of action of these compounds suggests importance of the presence of unsubstituted 3,4 double bond in the molecule2 and possible formation of 3,4-epoxide3 of precocenes via the diol4,5 which might be the species responsible for the anti JH activity.

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