Abstract

We synthesized poly-substituted pyrrole derivatives 4a– e, 7a– c and 10a– d from the reaction of phenacyl bromide and the aza-Baylis–Hillman adducts 1a– d or their rearranged derivatives 5a– e. The pyrroles were synthesized via the successive N-alkylation, Michael addition, elimination of p-toluenesulfinic acid and oxidative aromatization processes.

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