Synthesis of Phenylethanoid Nanoparticle and Study of Its Antibacterial Effect

Abstract

Phenylethanoid nanoparticles has been hypothesized to exert wide range of biological effects, one of them antimicrobial. phenylethanoid acts as free radical-scavenger and metal-chelator. Today, there is a considerable interest in it because it is safe, nontoxic. The generation of Phenylethanoid nanoparticles was confirmed by change of Phenylethanoid extract color from brown. Bovine fecal samples were collected by direct rectal retrieval using disposable gloves, isolation and identification of E. coli , Nanoparticles of phenylethanoid of were prepared by the nanoprecipitation method according to Gaonkar,Jasim et al., evaluation was done by agar well diffusion method. Highly antibacterial activity was recorded in comparison to plant extract. The antibacterial activity of Phenylethanoid was evaluated by agar well diffusion method. Six isolates of E. coli were identified and all of them were showed inhibition zones from 16-20 mm. From this study, the antibacterial activity of Phenylethanoidwas more efficient to eradicate. The goal of current study is to eradicate pathogenic bacteria (Escherichia coli ) that isolated from bovis feces infected with diarrhea by alternative treatment Phenylethanoid nanoparticles.