Synthesis of orthoaminocarbonitrile tetrahydronaphthalenes catalyzed by butyl-3-methylimidazolium hexafluorophosphate ionic liquid base catalyst

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In this research, the treatment of cyclohexanone, malononitrile, and aromatic aldehydes was carried out for the successful synthesis of orthoaminocarbonitrile tetrahydronaphthalenes by using butyl-3-methylimidazolium hexafluorophosphate as a base catalyst. In this protocol, the target products were obtained in high to excellent yields between 85% and 95% and short reaction times between 10 and 20 min under mild conditions. All products were identified by the melting points, FT-IR, and 1H NMR techniques.