Abstract
We report the synthesis and bioactivity studies of 3-dimensional macro-porous material produced by thermal treatment of organic–inorganic hybrid composite. This is prepared by sol–gel processing of co-poly(methylmethacrylate (MMA)-vinyltriethoxysilane (VTS)) with tetraethoxysilane (TEOS), calcium nitrate and zinc nitrate, ([CH 2C(CH 3)(CO 2CH 3)] 0.8n-[CH 2-CH(Si(OEt) 3] 0.2n-SiO 2-CaO-ZnO) ( 1). Thermal treatment of this polymer at 600 °C yielded macro-porous bioglass monolith, with pore size distribution between 1 and 5 μm and showed excellent bone bonding ability in simulated body fluid. The ratio of VTS:MMA in the organic polymer can easily be controlled. Since the VTS is the bonding agent, the amount of VTS in the co-polymer can be utilized to increase or decrease the porosity of the hybrid composite. This may be a convenient approach for preparation of bioglass scaffolds especially in tissue engineering of bone.
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