Synthesis of Ag-Containing CaO-SiO2 Gel and its Apatite Forming Ability in Simulated Body Fluid

Abstract

We reported the apatite-forming ability of CaO-SiO2 spherical particles obtained through a sol-gel processing. In this study, we synthesized the CaO-SiO2 containing silver (Ag) ions using silver standard solution to induce antibacterial property and evaluated the effects of Ag on their apatite forming ability in a simulated body fluid (SBF). The particles with 30CaO·70SiO2 starting composition in Ag standard solution with range 0 to 500 ppm Ag content were synthesized through the sol-gel processing. The prepared 30CaO·70SiO2 could be obtained as spherical particles with regardless of Ag contents. The prepared Ag-contained 30CaO·70SiO2 particles formed apatite on their surfaces after soaking in SBF regardless of Ag contents. Consequently, Ag-contained 30CaO·70SiO2 spherical particle could be obtained without decrease of its apatite forming ability.