Abstract
Employing a flexible synthetic strategy towards laurenditerpenol, two analogues featuring the 7- oxabicyclo[2.2.1]heptane ring system present in the natural product have been prepared and their ability to inhibit HIF-1 activation has been evaluated. Their weak activity indicates the importance of the cyclohexenol part of the prototype. Keywords: Furan, Diels-Alder reaction, Olefin cross-metathesis, Natural products
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