Synthesis of highly electroactive nanoflowers like manganesetin oxide and electroanalytical application for chloramphenicol determination in milk and honey samples

Abstract

Abstract In this report, we have described the disposable electrochemical sensor for the detection of chloramphenicol (CMP) based on MnSnO3 NFs (MSO NFs) modified glassy carbon electrode (GCE). MSO NFs were successfully synthesized through a simple and low-cost coprecipitation approach. FE-SEM, HR-TEM, FTIR, and XRD are used to examine the physical and chemical properties of as-synthesized MSO NFs. The electrochemical activity and performance of the proposed electrode towards the CMP sensor is explored by electrochemical techniques namely CV and DPV. The MSO NFs fabricated electrode showed a rapid current response towards CMP reduction. Under the optimum condition, a linear range is 0.003 μM to 92.21 μM, with low detection limit is calculated is 1 nM. In addition, the proposed sensor has achieved good reproducibility, and excellent selectivity, long-term stability. It was applied to the determination of CMP in spiked milk and honey food samples with satisfactory results. This result demonstrated the MSO NFs was potentially possible for practical applications. All these features, suggest that the MSO NFs is a promising candidate as a new class of electrocatalyst for the highly selective electrochemical sensor for CMP.