Abstract
AbstractA palladium‐catalyzed cascade reaction has been realized for the synthesis of 5H‐pyrrolo[2,3‐b]pyrazines and 5H‐pyrazino[2,3‐b]indoles from benzyl isocyanide by choosing o‐pivaloyloximes or o‐iodoanilines as a suitable substrate. The key steps involved are (i) oxidative addition of palladium through N–O or C–I cleavage; (ii) migratory double isocyanide insertion; and (iii) cross‐dehydrogenative coupling. Notable features are good functional group tolerance as well as formation of three C–C and one C–N bonds.magnified image
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
