Abstract
A novel class of substituted quinolines was synthesized through a one-pot, four-component sequential reaction by intramolecular C–H activation of isocyanides with N-sulfonylamidines, catalyzed by copper(I) iodide and l-proline as a ligand in acetonitrile at room temperature. The readily available starting materials, no need for column chromatography, mild catalytic conditions, and moderate to high yields are important features of this simple one-pot reaction.
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