Abstract

A series of twenty ethylene oxide and propylene oxide addition polymers of ursolic acid and some of its derivatives have been made and characterized. In addition, an ethylene oxide and propylene oxide polymer of cholic acid and ethylene oxide polymers of vitamin A, vitamin D 2 , vitamin E, cortisone, estradiol, and testosterone are reported. Attempts to prepare steroidal polymers with highly branched or crosslinked side chains by using glycidol and epichlorhydrin were unsuccessful. The most acceptable structures as determined from molecular weight and solubility data were determined. Percentage polyalkylene oxide content, solubilities, and molecular weight or chain length distributions are presented.

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