Abstract
AbstractTwo new procedures are described for the preparation of di‐ and tetra‐deuterated 10‐[[3‐[4‐(2‐hydroxyethyl)‐1‐piperazinyl]propyl]]‐2‐trifluoromethyl‐10H‐phenothiazine (fluphenazine). Deuterium was introduced in either the 1‐ or the 1‐ and 3‐positions of the propyl side chain by reduction with deuterated borane in tetrahydrofuran of the appropriately substituted N‐10 amide or amido ester. The isotopic purity of the synthesized deuterated products was greater than 99%.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of Labelled Compounds and Radiopharmaceuticals
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
