Abstract
In this report, the mild synthetic strategies for the synthesis of two series of boron-containing tetrazoles were included. For the first series, a boron-containing isocyanide reacted with TMS-N3 to afford the desire products. The reaction took place at 60 °C in TFE for 30 min under microwave irradiation. For the second series, the Ugi four-component reaction (Ugi-4CR) was deployed to synthesize the desire products. The reaction took place simply in MeOH at ambient temperature for 2 h. The synthetic strategies included could provide access to ranges of boron-containing tetrazole libraries, which might possess unique biological properties.
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