Abstract
The synthesis of the 14-amino-6, 7-dihydro-12H-benzo[f]indolo[2, 3-a] quinolizinium chloride (2a) and substituted derivatives is described. The compounds were evaluated as inhibitors of protein kinase CKII and structure-activity relationships were studied. The most potent compound was 14-amino-6, 7-dihydro-12H-4-chlorobenzo[f]indolo-[2, 3-a]quinolizinium chloride (2e) with an IC50 of 0.0064 mM.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
