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https://doi.org/10.1080/00397919508010790
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Cite Journal: Synthetic Communications |  Publication Date: Jan 1, 1995 |
 Citations: 33 |
Affiliation: Research Triangle Park Foundation, RTI International
Abstract A practical synthesis of epibatidine (1) was developed. The key step involved selective reduction of the 5,6-double bond of 7-(tert-butyloxy-carbonyl)-2-(2-chloro-5-pyridyl)-3-(phenylsulfonyl)-7-azabicyclo[2.2.1]-heptane-2,5-diene (4) using nickel boride.
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