Abstract

In this research, AgO–TiO2 nanocomposites have been synthesized through a simple method. Besides, silver nitrate, and tetra-n-butyl titanate, as starting reagents were applied. The as-synthesized products were characterized by powder X-ray diffraction analysis, scanning electron microscopy, vibrating sample magnetometer, fourier transform infrared spectroscopy, and energy-dispersive X-ray spectroscopy techniques. Furthermore, antibacterial effects of synthesized AgO–TiO2 nanoparticles against Escherchia coli (ATCC 25922) and Staphylococcus aureus (ATCC 25923) were studied by determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values, using micro broth dilution method according to Clinical and Laboratory Standards Institute (CLSI) guidelines. The MIC and MBC values of AgO–TiO2 nanoparticles were found to be 24 and 48 µg/ml for E. coli and 24 and 24 µg/ml for S. aureus respectively. Theses result showed our synthesized nanoparticles have efficient antibacterial activity especially against gram positive bacteria.

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