Abstract

New pyrazolo[1,5-a][1,3,5]triazines with a heteroaromatic substituent in position 4 and dichloromethyl moiety in position 2 were obtained via a heterocyclization reaction of readily available reagents - N-(2,2-dichloro-1-cyanoethenyl)carboxamides and 3(5)-aminopyrazoles. The high efficiency of the proposed method for the synthesis of 2-(dichloromethyl)-pyrazolo[1,5-a][1,3,5]triazines with furan-2-yl, thien-2-yl, and pyridine-3-yl substituents was demonstrated.

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