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https://doi.org/10.1021/jo062176a
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Cite Journal: The Journal of Organic Chemistry |  Publication Date: Dec 30, 2006 |
 Citations: 18 |
Affiliation: KU Leuven
A simple and catalyst-free method for the synthesis of phosphonated 2(1H)-pyrazinones is described starting from 3,5-dichloropyrazinones. The method also works for 3-bromo- and 3-iodopyrazinones. Classical heating conditions as well as microwave-enhanced reaction conditions were tested.
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