Abstract

Various 2-[5-(aryl)-1,2,4-oxadiazol-3-yl]quinazolin-4(3H)-ones have been synthesized from the reaction of diaminoglyoxime-based nitrones with methyl 2-aminobenzoate or 2-aminobenzamide in the presence of acetic acid at 100 °C. The reaction was extended as a one-pot three-component approach starting from diaminoglyoxime, aldehyde and methyl 2-aminobenzoate.

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